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Cardiac output response to altered acid-base status during diethyl ether anaesthesia.
Metadata
JournalCan Anaesth Soc JNot FoundDate
1975-Nov
Publication Type
Journal Article
Volume
1975-Nov / 22 : 673-9
Author
Sodipo JO , Lee DC , Morris LE
DoiPMIDMESH
Acid-Base Equilibrium
Acidosis
Acidosis, Respiratory
Alkalosis
Alkalosis, Respiratory
Anesthesia, Inhalation
Animals
Bicarbonates
Blood
Carbon Dioxide
Cardiac Output
Dogs
Ether
Ethyl Ethers
Hydrochloric Acid
Hydrogen-Ion Concentration
Hypoxia
Male
Oxygen
Abstract
The effects of acid-base changes on cardiac output during diethyl ether anaesthesia were studied in 25 mongrel dogs prepared by surgically implanting a plastic encased non-ferrous core electromagnetic probe on the ascending aorta. The findings are: (1) Metabolic acidaemia produced only slight decrease in cardiac output but a more marked fall became evident with decreasing pH(2) Respiratory acidaemia led to a slight rise in cardiac output. (3) Respiratory alkalaemia decreased cardiac output. (4) Metabolic alkalaemia also produced a decline in cardiac output.
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Can Anaesth Soc JCanadian Anaesthetists' Society journal
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