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alpha-Naphthoflavone activation of 6-hydroxymethylbenzo(alpha)pyrene synthetase.
Metadata
Journalcancer research9.727Date
1975-Dec
Publication Type
Journal Article
Volume
1975-Dec / 35 : 3731-4
Author
Sloane NH
Doi
Not Found
PMIDMESH
Animals
Benzoflavones
Benzopyrenes
Enzyme Activation
Flavonoids
Hydrogen-Ion Concentration
Hydroxymethyl and Formyl Transferases
Lung
Membranes
Microsomes
Microsomes, Liver
Rats
Transferases
Abstract
alpha-Naphthoflavone activates the aryl hydroxymethyl synthetase of both the microsomal membrane-bound and soluble enzymes of rat liver and rat lung. The enzyme catalyzes the hydroxymethylation of benzo(alpha)pyrene to the 6-hydroxymethyl derivative.
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9.7
Cancer Rescancer research
Metadata
LocationUnited States
FromAMER ASSOC CANCER RESEARCH

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