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[Basic phospholipase of Naja nigricollis venom].
Metadata
JournalC.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat.Not FoundDate
1975-Apr-07
Publication Type
Journal Article
English Abstract
Volume
1975-Apr-07 / 280 : 1633-5
Author
Dumarey C , Sket D , Joseph D , Boquet P
Doi
Not Found
PMIDMESH
Amino Acids
Animals
Hydrogen-Ion Concentration
Lethal Dose 50
Mice
Phosphatidylcholines
Phospholipases
Rabbits
Snake Venoms
Abstract
It is confirmed that N. nigricollis venom contains several phospholipases one of these is a basic phospholipase A. This enzyme is toxic for mice when injected intravenously. In vitro it reacts on egg yolk lecithin producing lysolecithin and prevents the phenomenon of blood clotting. An immunological identity has been established between this basic phospholipase and two acidic phospholipases present in the same venom.
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C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat.Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles
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