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Effects of graded infusions of monomethylmethacrylate on coagulation, blood lipids, respiration and circulation. An experimental study in dogs.
Metadata
Journalclinical orthopaedics and related research4.329Date
1975-Nov-Dec
Publication Type
Journal Article
Volume
1975-Nov-Dec / : 187-97
Author
Modig J , Busch C , Waernbaum G
DoiPMIDMESH
Animals
Blood Coagulation
Blood Pressure
Bone Cements
Collateral Circulation
Dogs
Hydrogen-Ion Concentration
Infusions, Parenteral
Lipids
Lung
Methylmethacrylates
Respiration
Abstract
In 4 dogs injected intravenously (i.v.) with 125I labeled fibrinogen, 51Cr labeled platelets and 99mTc labeled albumin, and subjected to successively increasing amounts of i.v. infused monomethylmethacrylate, doses corresponding to the amounts released into the blood stream following implantation of acrylic cement during total hip replacements did not affect the clotting mechanism, did not cause trapping of platelets and fibrin in the lungs, did not generate fat emboli, and did not cause depression of the arterial oxygen tension or blood pressure. Monomethylmethacrylate in whole blood was associated with both blood cells and plasma.
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Clin Orthop Relat Resclinical orthopaedics and related research
Metadata
LocationUnited States
FromLIPPINCOTT WILLIAMS & WILKINS

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