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[Biochemical studies on camomile components/III. In vitro studies about the antipeptic activity of (--)-alpha-bisabolol (author's transl)].
Metadata
JournalArzneimittelforschungNot FoundDate
1975-Sep
Publication Type
Journal Article
English Abstract
Volume
1975-Sep / 25 : 1352-4
Author
Isaac O , Thiemer K
Doi
Not Found
PMIDMESH
Dose-Response Relationship, Drug
Hemoglobins
Hydrogen-Ion Concentration
In Vitro Techniques
Methods
Pepsin A
Plants, Medicinal
Sesquiterpenes
Spectrophotometry, Ultraviolet
Trichloroacetic Acid
Tyrosine
Abstract
(--)-alpha-Bisabolol has a primary antipeptic action depending on dosage, which is not caused by an alteration of the pH-value. The proteolytic activity of pepsin is reduced by 50 percent through addition of bisabolol in the ratio of 1/0.5. The antipeptic action of bisabolol only occurs in case of direct contact. In case of a previous contact with the substrate, the inhibiting effect is lost.
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