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Uveal Melanoma in an Aradi Goat (Capra aegagrus hircus).
Metadata
Journaljournal of comparative pathology0.994Date
2020 Apr 22
3 months ago
Publication Type
Journal Article
Volume
2020-May / 177 : 5-9
Author
El-Shafaey E 1, Hamed MF 2
Affiliation
  • 2. Department of Pathology, Faculty of Veterinary Medicine, Mansoura University, Dakahlia, Egypt. Electronic address: [email protected]
Doi
PMIDMESH
Abstract
A 6-year-old Aradi goat (Capra aegagrus hircus) was admitted with glaucoma of the left eye. Blood clots and a yellow exudate covered the cornea and sclera. Ocular examination found glaucoma, exophthalmos and a distorted iris. Because of the blindness and pain, surgical enucleation of the left eye was performed. Gross examination through the mid-sagittal section of the enucleated globe revealed a pigmented mass occupying the anterior chamber. It had invaded the peripheral cornea and extended to the dorsal iris. Histologically, the mass was composed of pleomorphic, epithelioid neoplastic cells with high-grade cellular atypia. Scattered cells contained brown-black pigment. Bleached sections demonstrated 6-7 mitoses per 10 high-power fields and the cornea displayed squamous metaplasia resembling that of skin. Immunohistochemistry revealed positive immunoreactivity of the tumour cells for vimentin, S100 and melan-A, confirming the diagnosis of uveal melanoma. This finding should be included in the differential diagnosis of ocular tumours causing glaucoma in goats.
Keywords: goat melan-A melanoma uvea
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J Comp Patholjournal of comparative pathology
Metadata
LocationEngland
FromELSEVIER SCI LTD

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