Hospital-acquired infections increase cost, morbidity, and mortality for patients across the United States and the world. Principal among these infections are central line-associated bloodstream infection, catheter-associated urinary tract infection, Clostridioides difficile, and methicillin-resistant Staphylococcus aureus colonization and infections. This article provides succinct summaries of the background, epidemiology, diagnosis, and treatment of these conditions. In addition, novel prevention strategies, including those related to recent national interventions, are reviewed.
Keywords: Bloodstream infection Catheter-associated urinary tract infection (CAUTI) Central line–associated bloodstream infection (CLABSI) Clostridioides difficile colitis Hospital-acquired infection Methicillin-resistant Staphylococcus aureus Urinary tract infection