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Clinical usefulness of very high serum soluble interleukin-2 receptor levels for the detection of tuberculous peritonitis in a patient with chronic myelogenous leukemia.
Metadata
Journaljournal of infection and chemotherapy1.722Date
2020 Jun 03
4 months ago
Type
Case Report
Volume
2020-Oct / 26 : 1054-1057
Author
Moriguchi M 1, Koh H 2, Hayashi T 1, Okamura H 1, Nanno S 1, Nakashima Y 1, Nakane T 1, Imoto W 3, Yamada K 3, Kakeya H 3, Hino M 1, Nakamae H 1
Affiliation
  • 2. Hematology, Graduate School of Medicine, Osaka City University, Osaka, Japan. Electronic address: [email protected]
  • 3. Department of Infection Control Science, Graduate School of Medicine, Osaka City University, Osaka, Japan; Research Center for Infectious Disease Sciences (RCIDS), Graduate School of Medicine, Osaka City University, Osaka, Japan.
Doi
PMIDMESH
Abstract
Tuberculous peritonitis is difficult to diagnose due to the disadvantages of ascitic culture and peritoneal biopsy. Although previous reports suggested that very high serum soluble interleukin-2 receptor (sIL-2R) levels may reflect the clinical activity of tuberculosis, little is known about the diagnostic utility of serum sIL-2R for tuberculous peritonitis. We describe a case of tuberculous peritonitis with chronic myelogenous leukemia. The abnormally high serum sIL-2R value and negative findings for other possible causes including lymphoma suggested tuberculous peritonitis and we administered anti-tuberculosis treatment before definitive diagnosis. Abnormally high serum sIL-2R levels may contribute to earlier diagnosis of tuberculous peritonitis, along with ruling out other potential differential diagnoses.
Keywords: Ascites Chronic myelogenous leukemia Soluble interleukin-2 receptor Tuberculosis Tuberculous peritonitis
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J Infect Chemotherjournal of infection and chemotherapy
Metadata
LocationNetherlands
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