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Gastrointestinal malignancy in cystic fibrosis.
Metadata
Journalpaediatric respiratory reviews2.716Date
2020 Apr 09
6 months ago
Type
Review
Journal Article
Volume
2020-Sep / 35 : 90-92
Author
Hough NE 1, Chapman SJ 2, Flight WG 2
Affiliation
  • 2. Oxford Adult Cystic Fibrosis Unit, John Radcliffe Hospital, Oxford, Headley Way, Oxford OX3 9DU, United Kingdom.
Doi
PMIDMESH
Abstract
Cystic fibrosis (CF) is a multisystem disease affecting the gastrointestinal (GI) tract as well as the lungs. As survival has increased significantly over the past few decades, complications not seen previously have become apparent. There is an overall increased rate of malignancy in CF, particularly from the GI tract and in the post-transplant population. The most common sites of malignancy are the pancreatico-biliary and digestive tract, as well as an increased rate of testicular cancer. Using an illustrative case of metastatic oesophageal malignancy which initially appeared to be hepatic in origin, we have reviewed the literature surrounding malignancy in CF with a particular focus on the GI tract.
Keywords: Cancer screening Colon cancer Cystic fibrosis Metastases Oesophageal cancer
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Paediatr Respir Revpaediatric respiratory reviews
Metadata
LocationEngland
FromELSEVIER SCI LTD

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