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Classical and Nonclassical Intercellular Communication in Senescence and Ageing.
Metadata
Journaltrends in cell biology16.041Date
2020 Jun 03
4 months ago
Type
Review
Journal Article
Volume
2020-Aug / 30 : 628-639
Author
Fafián-Labora JA 1, O'Loghlen A 2
Affiliation
  • 2. Epigenetics and Cellular Senescence Group, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, UK. Electronic address: [email protected]
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PMIDMESH
Abstract
Intercellular communication refers to the different ways through which cells communicate with each other and transfer a variety of messages. These communication methods involve a number of different processes that occur individually or simultaneously, which change depending on the physiological or pathological context. The best characterized means of intercellular communication is the release of soluble factors that affect the function of neighboring cells. However, there are many other ways by which cells can communicate with each other. Here, we review the different means of intercellular communication including soluble factors in the context of senescence, ageing, and age-related diseases.
Keywords: SASP ageing extracellular vesicles intercellular communication metabolites senescence
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Trends Cell Bioltrends in cell biology
Metadata
LocationEngland
FromELSEVIER SCIENCE LONDON

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