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Diagnostic and therapeutic problems of polyarteritis nodosa.
Metadata
Journalsamj south african medical journal1.285Date
1979-Oct-13
Type
Journal Article
Comparative Study
Volume
1979-Oct-13 / 56 : 634-7
Author
Keeton GR
Doi
Not Found
PMIDMESH
Adult
Female
Humans
Male
Middle Aged
Polyarteritis Nodosa
Time Factors
Abstract
Eleven patients with a diagnosis of polyarteritis nodosa were seen over an 8-year period in Cape Town, and evaluated as to clinical presentation, the most effective diagnostic approach, and the response to therapy. The major features of fever, abdominal pain, peripheral neuritis, myalgia/arthralgia, weight loss, proteinuria, positive urinary sediment and high white blood cell count should readily lead to the diagnosis which can be confirmed by multiple muscle biopsies. At the same time an ellipse of skin and subcutaneous fat can be taken. If the diagnosis is made early enough, an aggressive approach to therapy with steroid and immunosuppressive drugs can induce a response even in those patients who already have renal failure.
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S Afr Med Jsamj south african medical journal
Metadata
LocationSouth Africa
FromSA MEDICAL ASSOC

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