MedicGo
Plasma vasopressin levels during haemorrhage in mature and immature fetal sheep.
Metadata
JournalJ. Dev. Physiol.Not FoundDate
1979-Feb
Type
Research Support, Non-U.S. Gov't
Journal Article
Volume
1979-Feb / 1 : 91-101
Author
Rurak DW
Doi
Not Found
PMIDMESH
Animals
Blood Pressure
Female
Fetal Blood
Fetus
Heart Rate
Hemorrhage
Hydrogen-Ion Concentration
Pregnancy
Sheep
Time Factors
Vasopressins
Abstract
In four mature chronically catheterized fetal sheep in utero arterial pressure, heart rate, arterial pH and haematocrit fell during a 16-70% haemorrhage, while Pao2 rose. Plasma vasopressin concentrations increased and were correlated with the percentage of blood volume removed. Following haemorrhage arterial pressure and heart rate were restored within 60 min, while hyperozaemia and acidaemia persisted. Plasma antidiuretic hormone (ADH) concentrations remained the same or increased and were significantly related to the degree of acidaemia. Upon return of the removed blood, pressure rose transiently and Pao2 fell; pH remained low and plasma ADH concentrations fell, but were still related to the degree of acidaemia. In three immature, exteriorized fetuses (0.4 of term) plasma vasopressin concentrations also rose during haemorrhage. The results indicate that fetal plasma vasopressin levels rise during haemorrhage in response both to hypovolaemia and the subsequent acidaemia. Further the response to haemorrhage is present at an early gestational age.
Fav
Like
Download
Share
Export
Cite
J
J. Dev. Physiol.Journal of developmental physiology
Metadata
Location
From

No Data

© 2017 - 2020 Medicgo
Powered by some medical students