MedicGo
Ion movements during energy-linked mitochondrial structural changes.
Metadata
Journaljournal of bioenergetics and biomembranes2.524Date
1978-Apr
Type
Journal Article
Volume
1978-Apr / 10 : 23-44
Author
Webster KA , Bronk JR
DoiPMIDMESH
Adenosine Diphosphate
Anaerobiosis
Animals
Cations, Monovalent
Hydrogen-Ion Concentration
Intracellular Membranes
Male
Microscopy, Electron
Mitochondria, Liver
Oxygen Consumption
Phosphates
Potassium
Rats
Sodium
Valinomycin
Abstract
The structure of isolated rat liver mitochondria has been observed in the electron microscope following incubation of the mitochondria in vitro under a variety of conditions. The results show that ultrastructural changes are only associated with the energization and deenergization of isolated mitochondria if the composition of the incubation medium permits ion movements in or out of the matrix. The mechanism of energy coupling does not appear to depend on these major mitochondrial structural changes. The addition of low levels of valinomycin greatly increases the rate at which the matrix compartment swells and shrinks on energization and deenergization even at low K+ concentrations.
Fav
Like
Download
Share
Export
Cite
2.5
J Bioenerg Biomembrjournal of bioenergetics and biomembranes
Metadata
LocationUnited States
FromSPRINGER/PLENUM PUBLISHERS

No Data

© 2017 - 2020 Medicgo
Powered by some medical students