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[A study of gamma-glutamyl-transpeptidase and of the ratio of IgA to transferrin in the pregnant woman (and when using oral contraception) and in the newborn (author's transl)].
Metadata
JournalJ Gynecol Obstet Biol Reprod (Paris)Not FoundDate
1979
Type
Journal Article
English Abstract
Volume
1979 / 8 : 625-30
Author
Crépin G , Querleu D , Delahousse G , Tassart M , Bonte M , Bonte-Lecomte D
Doi
Not Found
PMIDMESH
Contraceptives, Oral
Female
Humans
Immunoglobulin A
Infant, Newborn
Pregnancy
Pregnancy Trimester, Third
Transferrin
gamma-Glutamyltransferase
Abstract
The authors confirm the absence of a marked variation in levels of gamma-glutamyl-transpeptidase in women under the influence of oestrogens, but a considerable rise in this enzyme in the newborn, particularly after delivery following vaginal obstetrical manoeuvre. They base these findings on 242 samples taken from pregnant women in the 3 trimesters of normal pregnancies and after delivery, and in the cord blood of newborn infants as well as in patients taking oral contraception. There is a slight rise in the levels of immunoglobulins A in the 3rd trimester of pregnancy. The overall rise in the blood levels of transferrin under the effect of oestrogens is confirmed. Norms were obtained for the levels of the IgA/T ratio which drops progressively as pregnancy progresses and with oral contraception. It has been found that in the last two trimesters the upper limit of the normal is 1 for the IgA/T ratio as compared with 1.9 in the general population. The study of these constants is of value when screening for maternal alcoholism and as a consequence for the prevention of the fetal alcohol syndrome.
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J Gynecol Obstet Biol Reprod (Paris)Journal de gynecologie, obstetrique et biologie de la reproduction
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