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Effect of protein on titrimetry of bicarbonate, titratable acid, and ammonium in urine.
Metadata
Journalclinical chemistry7.292Date
1979-Mar
Type
Journal Article
Volume
1979-Mar / 25 : 362-5
Author
Litkowski LJ , Wilson TL
Doi
Not Found
PMIDMESH
Acid-Base Equilibrium
Ammonia
Bicarbonates
Humans
Hydrogen-Ion Concentration
Methods
Proteinuria
Urine
Abstract
Measurement of bicarbonate, titratable acid (HTA+) and ammonium in the urine can facilitate clinical evaluation of acid-base status. Sequential measurement of these three components by titrimetric techniques is well established, but possible interference by proteinuria has not been examined. We report the influence on these analyses of albumin and globulin, two proteins commonly observed in urine in renal disease states. The presence of these proteins in urine affects the measurement of NH4+, and to a less extent that of HTA+. The magnitude of the effect depends on the concentration and the kind of protein present. Proteins do not influence the measurement of HCO3-.
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7.3
Clin Chemclinical chemistry
Metadata
LocationEngland
FromOXFORD UNIV PRESS INC

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