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K+ conductance modified by a titratable group accessible to protons from the intracellular side of the squid axon membrane.
Metadata
Journalbiophysical journal3.854Date
1979-May
Type
Journal Article
Volume
1979-May / 26 : 319-24
Author
Wanke E , Carbone E , Testa PL
DoiPMIDMESH
Animals
Axons
Cell Membrane
Decapodiformes
Electric Conductivity
Hydrogen-Ion Concentration
Ion Channels
Kinetics
Potassium
Abstract
In the range of pH examined (5.2-10), variations of internal pH from high to low values result in a reversible decrease of the conductance of the open K channels, without significantly affecting the kinetics parameters. A linear plot of the conductance versus internal pH suggests the existence of a titratable group that has an apparent pKa of about 6.9, and that is accessible to protons only from the intracellular side of the membrane.
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3.9
Biophys Jbiophysical journal
Metadata
LocationUnited States
FromCELL PRESS

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