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The lower esophageal sphincter in gastroesophageal reflux in children.
Metadata
Journaljournal of clinical gastroenterology2.973Date
1979-Jun
Type
Journal Article
Comparative Study
Volume
1979-Jun / 1 : 119-23
Author
Herbst JJ , Book LS , Johnson DG , Jolley S
DoiPMIDMESH
Age Factors
Esophagogastric Junction
Gastroesophageal Reflux
Humans
Hydrogen-Ion Concentration
Infant
Infant, Newborn
Pressure
Respiratory Tract Diseases
Abstract
Esophageal function was evaluated in 51 children less than 2 years of age with radiologic evidence of gastroesophageal reflux. Detection of an acid esophageal pH was a sensitive measure of gastroesophageal reflux. Lower esophageal sphincter pressures were greater in reflux patients with respiratory symptoms (18.0 +/- 1.4 mm Hg) than in reflux patients without respiratory symptoms (9.5 +/- 1.0 mm Hg). The intra-abdominal segment of the lower esophageal sphincter was shorter in patients with reflux than in controls (0.51 +/- 0.05 cm vs. 0.75 +/- 0.08 cm). It was also shorter in patients requiring surgical therapy (0.34 +/- 0.05 cm) than in those responding to medical therapy (0.63 +/- 0.07 cm).
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J Clin Gastroenteroljournal of clinical gastroenterology
Metadata
LocationUnited States
FromLIPPINCOTT WILLIAMS & WILKINS

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