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Plasma hypoxanthine in neonatal hypoxia: a comparison of two methods.
Metadata
Journaleuropean journal of obstetrics & gynecology and reproductive biology1.868Date
1978-Apr
Type
Journal Article
Comparative Study
Volume
1978-Apr / 8 : 89-94
Author
Guicheney P , Zorn JR , Rey E , Sureau C , Olive G
DoiPMIDMESH
Blood Gas Analysis
Chromatography, High Pressure Liquid
Female
Fetal Blood
Humans
Hydrogen-Ion Concentration
Hypoxanthine
Hypoxanthines
Hypoxia
Infant, Newborn
Partial Pressure
Pregnancy
Abstract
Hypoxanthine levels were determined in both venous and arterial cord blood of 42 neonates. Two methods were compared, a PO2 electrode determination and an HPLC (high-pressure liquid chromatography) method. A good correlation was found between the two methods. However, the HPLC method was more sensitive, more reproducible and easier to perform. Hypoxanthine levels in the umbilical artery were found to be higher than in the vein. A significant negative correlation between pH and hypoxanthine level was established. The studies showed that plasma hypoxanthine levels by themselves did not provide an absolute diagnosis of intrauterine hypoxia.
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Eur J Obstet Gynecol Reprod Bioleuropean journal of obstetrics & gynecology and reproductive biology
Metadata
LocationIreland
FromELSEVIER

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