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Temperature sensitivity of DNA synthesis in mouse testicular germ cells in vitro.
Metadata
Journalexperimental cell research3.383Date
1978-May
Type
Journal Article
Volume
1978-May / 113 : 403-8
Author
Nishimune Y 1, Aizawa S
Affiliation

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Doi
PMIDMESH
Animals
Body Temperature
Cell Differentiation
Cryptorchidism
Culture Techniques
DNA Replication
Male
Mice
Mice, Inbred C57BL
Seminiferous Tubules
Spermatogonia
Temperature
Testis
Abstract
The effect of temperature on testicular DNA synthesis in mice was studied in vitro. By using cultures of cryptorchid testis, DNA synthesis of differentiated germ cells, such as intermediate and type B spermatogonia and resting primary spermatocytes, was shown to be temperature-sensitive, while that of undifferentiated type A spermatogonia was not. DNA synthesis of non-germ cells was not temperature-sensitive. This temperature sensitivity of germ cells in DNA synthesis may be one cause of the thermal inhibition of germ cell differentiation.
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3.4
Exp Cell Resexperimental cell research
Metadata
LocationUnited States
FromELSEVIER INC

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