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NAD-linked glutamate dehydrogenase in Trypanosoma cruzi.
Metadata
JournalComp. Biochem. Physiol., BNot FoundDate
1979
Type
Research Support, Non-U.S. Gov't
Journal Article
Volume
1979 / 64 : 129-31
Author
Cazzulo JJ 1, de Cazzulo BM , Higa AI , Segura EL
Affiliation

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Doi
PMIDMESH
Animals
Cell-Free System
Chromatography, Gel
Glutamate Dehydrogenase
NAD
NADP
Trypanosoma cruzi
Abstract
1. Epimastigotes of Trypanosoma cruzi, Tulahuén strain, contained a NAD-linked glutamate dehydrogenase (EC 1.4.1.3), in addition to the already known NADP-linked enzyme enzyme (EC 1.4.1.4). 2. The partially purified NAD-linked enzyme had a higher molecular weight and was much more labile than the NADP-linked enzyme, and was inhibited by purine nucleotides. 3. These results further emphasize the difference in glutamate metabolism between the parasite and its mammalian host.
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Comp. Biochem. Physiol., BComparative biochemistry and physiology. B, Comparative biochemistry
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