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Composition of glycoproteins secreted by tracheal explants from various animal species.
Metadata
JournalComp. Biochem. Physiol., BNot FoundDate
1979
Type
Journal Article
Comparative Study
Volume
1979 / 62 : 195-200
Author
Kaizu T 1, Lyons SA , Cross CE , Jennings MD , Last JA
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Doi
PMIDMESH
Animals
Bronchi
Chickens
Chromatography, DEAE-Cellulose
Dogs
Electrophoresis, Cellulose Acetate
Glycoproteins
Guinea Pigs
Humans
Hydrogen-Ion Concentration
Macaca mulatta
Mice
Mucus
Rats
Sheep
Swine
Trachea
Abstract
1. The acidic and neutral glycoproteins secreted by cultured tracheal explants from pigs, sheep, rats, mice, monkeys, guinea pigs, dogs and chickens were purified and fractionated by column chromatography on DEAE-cellulose and by electrophoresis on cellulose acetate. 2. The ratios of acidic to neutral mucus glycoproteins were compared for the above animals with that of mucus glycoproteins secreted by cultured human bronchi. 3. The observed ratios of acidic to neutral glycoproteins ranged from 4.0 (mouse) to 7.2 (chicken and pig) from cultured tracheae; secreted human bronchial mucus had a ratio of 2.7. 4. The ratio of acidic to neutral glycoproteins secreted by tracheal explants varied with duration of incubation of the trachea in culture.
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Comp. Biochem. Physiol., BComparative biochemistry and physiology. B, Comparative biochemistry
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