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The effects of drugs on the processes regulating the functional activity of brain monoamines.
Metadata
JournalProg NeuropsychopharmacolNot FoundDate
1979
Type
Review
Journal Article
Volume
1979 / 3 : 15-23
Author
Grahame-Smith DG 1
Affiliation

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Doi
PMIDMESH
Adrenergic beta-Antagonists
Animals
Behavior, Animal
Biogenic Monoamines
Blood Platelets
Brain Chemistry
Chlorpromazine
Dopamine
Electroshock
Humans
Serotonin
Abstract
1. By study of the synthesis and turnover of brain monoamines and with the use of behavioral models which indicate the functional activity of brain 5HT and dopamine, it is possible to unravel the mechanisms by which some drugs produce behavioral effects. 2. Using these techniques the acute and chronic effects of certain neuroleptics, propranolol and other beta-adrenergic blocking agents, repeated electroconvulsive shock, and lithium upon the functional activity of brain 5HT and dopamine are examined. 3. The clinical relevance of these studies is discussed.
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Prog NeuropsychopharmacolProgress in neuro-psychopharmacology
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